Introduction


Metilene3 is a software to identify differentially methylated regions (DMRs) and perform clustering based on DMRs among multiple samples/groups.

image info

Citation

Zhu, Z., Bernhart, S. H., Jühling, F., Kretzmer, H., & Hoffmann, S. (2026). metilene3: identifying DMRs across multiple conditions with auto-classification. Nature communications, 17(1), 5848. https://doi.org/10.1038/s41467-026-74931-y

License

The software is published under the GNU GPL v2.0 license.